With the longest section of the Great River Road, Illinois offers something for every traveler, whether you’re interested in exploring historical sites or discovering charming small towns along the Mississippi River.
Got an appetite? Illinois’ section of the Great River Road has plenty to fill your menu. Just take a look.
Start your day off right as you travel through Illinois’ Great Rivers Country with breakfast and a cup of coffee at Otto’s Place in Galena. Or, get your caffeine fix at Milltown Coffee in Moline.
Grab a meal with a great view of the Mississippi River at The Loading Dock in Grafton. (Fun photo op side trip: Visit Collinsville—just east of St. Louis—to snap a pic of the world’s largest catsup bottle.)
You’re in the Midwest, so why not partake in some farm-to-table deliciousness? In Galena, head to One Eleven Main for delectable dishes filled with local flavor. When you’re in Quincy, don’t miss the unique local plates at Thyme Square.
You’ll find wineries aplenty along the Great River Road in Illinois. Illinois’ Great Rivers Country offers a great look at the dozens of wineries you can visit between Galena and Cairo. Interested in distilled spirits? Visit Stumpy’s Spirits Distillery in Columbia or Blaum Bros Distilling Co. in Galena.
Discover delicious desserts and a true slice of Americana at Lagomarcino’s in Moline, where four generations of the Lagomarcino family have been serving up chocolates, candy and homemade ice cream. Are baked treats more your thing? Visit Kruta Bakery in Collinsville or Nauvoo Mill & Bakery.
(Photos courtesy of the Illinois Office of Tourism)
Exploring the Great River Road in Missouri will take you alongside scenic bluffs, through historic towns and into the bustling metropolis of St. Louis. It’s enough to make anyone hungry—here are some places to find some uniquely Missouri food in the Gateway City and beyond.
Hot Salami Sandwich
During the 20th century, St. Louis’s Italian neighborhood, The Hill, was a go-to for anyone looking for authentic cuisine d’Italia. Gioia’s Deli, one of the few remaining odes to The Hill’s glory days, opened its doors in 1918 and became famous for the hot salami sandwich. It’s no wonder this tried-and-true favorite has been named best sandwich in the city for years, as it’s served on a delicious garlic cheese bread and finished off with a spicy giardiniera. Get a taste of St. Louis’ cultural history and the famous hot salami sandwich during your visit and you’ll be a Gioia’s fan for life.
Gooey Butter Cake
It’s safe to say gooey butter cake is one of history’s tastiest mistakes. In the 1930s, a new employee at a St. Louis bakery accidentally swapped proportions of flour and butter in a cake recipe, and gooey butter cake was the result. Surprisingly, the dessert became a local favorite and bakeries around the city began mimicking the recipe. Try it at Park Avenue Coffee, a local chain that offers over 70 flavors of gooey butter cake.
St. Louis-style pizza
A trip to St. Louis requires trying the city’s rendition of pizza. St. Louis-style pizza is in a league of its own with a dense, cracker-like crust and a sweet sauce inspired by the area’s Sicilian immigrants. What really makes it unique is Provel cheese, a trademark combination of provolone, Swiss and white cheddar that is difficult to find anywhere outside St. Louis. Head to Imo’s for one of the best renditions of this quirky twist on a universally loved dish.
If you’re headed south on Missouri’s Great River Road, don’t miss the dining options in the charming towns of Ste. Genevieve (which also has several wineries nearby) and Cape Girardeau. Headed north, you can find tasty restaurants, breweries and more in Hannibal, the boyhood home of Mark Twain.
Whether St. Louis is the only destination on your itinerary, or you’re passing through on a trek down the Mississippi, the city is home to culinary quirks and combinations of culture that are worth making a stop.