The southern Great River Road is a region rich in history, culture, music, and outstanding food—here’s a closer look at some of the welcoming cities, towns and unique attractions you should visit as you’re traveling along the Great River Road in Arkansas, Kentucky, Tennessee, Mississippi, and Louisiana.

Kentucky

Kentucky is home to the shortest stretch of the Great River Road, but there is still plenty to see and do along the route. Head to Wickliffe Mounds State Historic Site to see earthen mounds created by the ancient people who inhabited the region in the 12th through 14th centuries. Take in amazing views of the Mississippi River and learn about the area’s Civil War history at Columbus-Belmont State Park.

Cities & towns to visit:

• Wickliffe: Located at the confluence of the Mississippi and Ohio rivers, Wickliffe is the seat of Ballard County and traces its founding to the 1880s, but people have lived in this scenic region overlooking the Mississippi River for nearly a thousand years

Interpretive Centers & Other Attractions:

• Wickliffe Mounds State Historic Site, Wickliffe
• Columbus-Belmont State Park, Columbus

Learn more about the Great River Road in Kentucky.

Tennessee

Photo: Tennessee Tourism

Tennessee’s section of the Great River Road offers a trip through outstanding scenery and engaging history. In the northwest corner of the state, visitors will find a state park at Reelfoot Lake, a 15,000-acre lake that is in actually a flooded forest (violent earthquakes in the region in 1811-12 formed the lake) and is a popular fishing and birdwatching spot. And don’t miss Memphis, which has long been a hub for music and culture in the country. 

Cities & towns to visit:

• Henning: This western Tennessee community has a strong connection to African American heritage (visit the Alex Haley Museum and Interpretive Center to learn about the “Roots” author) and is also home to great recreation options like the Mississippi River Corridor and Champion Lake
• Memphis: Music history (Sun Studio, Graceland, Beale Street, the Stax Museum of American Soul are just a few of the attractions you’ll find), delicious food (Memphis is famed for its barbeque), and recreation options abound in this Mississippi River hub in southwestern Tennessee

Interpretive Centers & Other Attractions:

• Reelfoot Lake State Park, Tiptonville
• National Civil Rights Museum, Memphis

Learn more about the Great River Road in Tennessee.

Arkansas

Photo: Arkansas Department of Parks, Heritage and Tourism

As the Great River Road passes through the Delta, you’ll see plenty of reasons Arkansas is known as “the Natural State.” From National Forests to wildlife refuges to hundreds of lakes—not to mention the Mississippi River itself—Arkansas’ Great River Road offers plenty of recreational opportunities. Visitors will learn plenty about the Delta’s history, too, whether they’re visiting Johnny Cash’s boyhood home or learning about the worst maritime disaster in U.S. history. 

Cities & towns to visit:

• Helena-West Helena: Formed when two existing towns merged, Helena-West Helena offers visitors a trip through Southern history; visit the Delta Cultural Center to learn more about the region and don’t miss the King Blues Biscuit festival in October
• Marianna: This small town southwest of Memphis is not only home to the scenic Mississippi River State Park and St. Francis National Forest, but also where you’ll find Jones Bar-B-Q Diner, a James Beard award-winning restaurant that’s one of the oldest black-owned restaurants in the country

Interpretive Centers & Other Attractions:

• Historic Dyess Colony – Johnny Cash Boyhood Home, Dyess
• Mississippi River State Park, Marianna
• Lake Chicot State Park, Lake Village

Learn more about the Great River Road in Arkansas.

Mississippi

Photo: Visit Mississippi

Take a trip through the history of the American South as you travel the Great River Road in Mississippi. Stop in Natchez—the oldest city on the Mississippi River—to tour antebellum homes and learn about the events that shaped this part of the country at Vicksburg National Military Park. Mississippi is a mecca for blues fans, too, who can find iconic attractions like Dockery Farms, the Delta Blues Museum, the B.B. King Museum and more.

Cities & towns to visit:

• Clarksdale: This can’t-miss destination for blues lovers is home to great live music venues and festivals, the engaging Delta Blues Museum, and the iconic “Devil’s Crossroads,” where bluesman Robert Johnson supposedly swapped his soul for his otherworldly talent
• Natchez: The oldest city on the Mississippi River was founded more than 300 years ago, and that history is evident today in its large collection of antebellum homes and traditional events like the Spring Pilgrimage and the Natchez Balloon Festival 

Interpretive Centers & Other Attractions

• Delta Blues Museum, Clarksdale
• GRAMMY Museum Mississippi, Cleveland
• Vicksburg National Military Park, Vicksburg

Learn more about the Great River Road in Mississippi.

Louisiana

Photo: Louisiana Office of Tourism

The Great River Road runs along both sides of the Mississippi River as it passes through Louisiana on its way to the Gulf of Mexico. Along the way, travelers will encounter historical river towns like Plaquemine and St. Francisville, as well as iconic cities like Baton Rouge and New Orleans. In the state’s far southeastern corner, you’ll find the unincorporated community of Venice, which marks the end of the Great River Road. 

Cities & towns to visit:

• Baton Rouge: Louisiana’s capital city was founded more than 300 years ago and its central location in the state still attracts legions of visitors who seek out the city’s great food, iconic history, and unique arts and culture
• New Orleans: No trip along the southern Great River Road is complete without a visit to New Orleans—whether you’re looking for historical sites, mouthwatering food, classic cocktails, great recreation options or pretty much anything else, you’ll find it in the Big Easy

Interpretive Centers & Other Attractions:

• Poverty Point – UNESCO World Heritage Site, Pioneer
• Louisiana Great River Road Interpretive Center and Museum, Darrow
• French Quarter, New Orleans

Learn more about the Great River Road in Louisiana.

Estimated travel times along the southern Great River Road:

• Wickliffe, KY to Tiptonville, TN: 1.25 hours
• Tiptonville, TN to Memphis, TN: 2 hours
• Memphis, TN to Clarksdale, MS: 1.5 hours
• Clarksdale, MS to Lake Village, AR: 1.75 hours
• Lake Village, AR to Vicksburg, MS: 1.75 hours
• Vicksburg, MS to Natchez, MS: 1.5 hours
• Natchez, MS to Baton Rouge, LA: 1.5 hours
• Baton Rouge, LA to New Orleans, LA: 1.75 hours
• New Orleans, LA to Venice, LA: 1.5 hours